Pages:
1/2/3/4/5/6/7/8/9
Chung Kuo Yao Li Hsueh Pao 1997 Mar;18(2):112-4
TRIAL - Rapid detoxification of heroin dependence by buprenorphine.
CONDUCTED BY - Liu ZM, Cai ZJ, Wang XP, Ge Y, Li CM
CONDUCTED AT
- National Institute on Drug Dependence, Beijing Medical University, China.
AIM: To evaluate the clinical efficacy of buprenorphine (Bup) in treatment of acute heroin withdrawal.
METHODS: Bup was given sublingually daily to 60 cases of heroin addicts in 3 groups: low, medium, and high doses. Clinical Institute Narcotic Assessment rated withdrawal signs and symptoms of heroin. Visual Analogue Scale assessed craving for heroin during detoxification. Treatment Emergent Symptom Scale assessed the side effects of Bup.
RESULTS: The mean daily consumption of Bup in low, medium, and high group was 2.0, 2.9, and 3.6 mg, respectively. Bup not only suppressed objective signs and withdrawal symptoms for heroin withdrawal, but also reduced the duration for heroin detoxification over 7-8 d.
CONCLUSION: Bup is an effective and rapid detoxification agent with fewer side effects for treatment of acute heroin withdrawal.
PMID:
10072959 ,
UI: 99172497
RUSAN
II ADDNOK